DrugRepV Browse Page

DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for Real-time PCR are 357

DrugRepV_ID	Antiviral Name	Drug type	Primary Indication	Secondary Indication	Strain	Pathways	Assay	Activity	Clinical Status	References
DrugRepV_0003	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	Brazilian strain ZKV2015	NA	Real-time PCR	Decrease (20 Fold)	Approved	29150641
DrugRepV_0021	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	GZ01, a recent Asian lineage	NA	Real-time PCR	Decrease (50 %)	Approved	29033372
DrugRepV_0022	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	GZ01, a recent Asian lineage	NA	Real-time PCR	Decrease (50 %)	Approved	29033372
DrugRepV_0023	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	FSS13025 strain (old Asian lineage)	NA	Real-time PCR	Decrease (50 %)	Approved	29033372
DrugRepV_0024	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	GZ01, a recent Asian lineage	NA	Real-time PCR	Decrease (2 Copies (10(6)/ml))	Approved	29033372
DrugRepV_0025	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	GZ01, a recent Asian lineage	NA	Real-time PCR	Decrease (1 Copies (10(6)/ml))	Approved	29033372
DrugRepV_0076	Bromocriptine	Nervous System	Parkinson disease	Zika virus	Puerto Rico strain PRVABC-59	NA	Real-time PCR	Decrease (4 Log viral titer (copies/ml))	Approved	28185815
DrugRepV_0079	Intron A	Antineoplastic and Immunomodulating Agents	Hairy cell leukemia | Malignant melanoma | AIDS-related Kaposi's sarcoma	Zika virus	Puerto Rico strain PRVABC-59	NA	Real-time PCR	Decrease (4 Log viral titer (copies/ml))	Approved	28185815
DrugRepV_0082	Avonex	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Zika virus	Puerto Rico strain PRVABC-59	NA	Real-time PCR	Decrease (5 Log viral titer (copies/ml))	Approved	28185815
DrugRepV_0085	Rebif	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Zika virus	Puerto Rico strain PRVABC-59	NA	Real-time PCR	Decrease (>4 Log viral titer (copies/ml))	Approved	28185815
DrugRepV_0088	Betaferon	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Zika virus	Puerto Rico strain PRVABC-59	NA	Real-time PCR	Decrease (5 Log viral titer (copies/ml))	Approved	28185815
DrugRepV_0091	Imukin	NA	NA	Zika virus	Puerto Rico strain PRVABC-59	NA	Real-time PCR	Decrease (>2 Log viral titer (copies/ml))	Approved, Investigational	28185815
DrugRepV_0177	Tenovin-1	Anticancer	Cancer	Zika virus	Mex2-81	NA	Real-time PCR	Decrease (80 %)	NA	28099856
DrugRepV_0178	Tenovin-1	Anticancer	Cancer	Zika virus	Mex2-81	NA	Real-time PCR	Decrease (85 %)	NA	28099856
DrugRepV_0179	Foretinib	Anticancer	Breast Cancer | Renal Cell Carcinoma | Breast Cancer	Zika virus	Mex2-81	NA	Real-time PCR	No significant effect (30 %)	Investigational	28099856
DrugRepV_0180	Foretinib	Anticancer	Breast Cancer | Renal Cell Carcinoma | Breast Cancer	Zika virus	Mex2-81	NA	Real-time PCR	No significant effect (0 %)	Investigational	28099856
DrugRepV_0181	Cabozantinib	Antineoplastic and Immunomodulating Agents	Cancer	Zika virus	Mex2-81	NA	Real-time PCR	Decrease (70 %)	Approved	28099856
DrugRepV_0182	Cabozantinib	Antineoplastic and Immunomodulating Agents	Cancer	Zika virus	Mex2-81	NA	Real-time PCR	No significant effect (20 %)	Approved	28099856
DrugRepV_0183	Nanchangmycin	Antibacterial; Antiviral	NA	Zika virus	Mex2-81	NA	Real-time PCR	Decrease (95 %)	NA	28099856
DrugRepV_0184	Nanchangmycin	Antibacterial; Antiviral	NA	Zika virus	Mex2-81	NA	Real-time PCR	Decrease (95 %)	NA	28099856
DrugRepV_0185	Nanchangmycin	Antibacterial; Antiviral	NA	Chikungunya virus	181/25	NA	Real-time PCR	Decrease (95 %)	NA	28099856
DrugRepV_0215	Ouabain	Cardiovascular agents	Atrial fibrillation and flutter | Heart failure	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (3.48 ± 0.21 Ct)	Approved	27801778
DrugRepV_0216	Ouabain	Cardiovascular agents	Atrial fibrillation and flutter | Heart failure	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?3.73 ± 4.88 Ct)	Approved	27801778
DrugRepV_0217	Alvespimycin	NA	Cancer	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (3.72 ± 0.18 Ct)	Investigational	27801778
DrugRepV_0218	Alvespimycin	NA	Cancer	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?0.63 ± 1.39 Ct)	Investigational	27801778
DrugRepV_0219	Bemcentinib	Anticancer	Cancer	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (3.05 ± 0.75 Ct)	Investigational	27801778
DrugRepV_0220	Bemcentinib	Anticancer	Cancer	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?1.83 ± 1.13 Ct)	Investigational	27801778
DrugRepV_0221	Zidovudine	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome/AIDS	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?3.12 ± 0.27 Ct)	Approved	27801778
DrugRepV_0222	Zidovudine	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome/AIDS	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?7.91 ± 2.67 Ct)	Approved	27801778
DrugRepV_0223	Didanosine	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?0.43 ± 3.87 Ct)	Approved	27801778
DrugRepV_0224	Didanosine	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?2.52 ± 1.27 Ct)	Approved	27801778
DrugRepV_0225	Stavudine	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?2.87 ± 0.22 Ct)	Approved, Investigational	27801778
DrugRepV_0226	Stavudine	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?3.93 ± 0.25 Ct)	Approved, Investigational	27801778
DrugRepV_0227	Abacavir Sulfate	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?1.54 ± 3.26 Ct)	Approved	27801778
DrugRepV_0228	Abacavir Sulfate	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?3.95 ± 2.69 Ct)	Approved	27801778
DrugRepV_0229	Entecavir	Antiinfectives For Systemic Use	Hepatitis B virus	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?3.08 ± 0.20 Ct)	Approved	27801778
DrugRepV_0230	Entecavir	Antiinfectives For Systemic Use	Hepatitis B virus	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?4.44 ± 1.11 Ct)	Approved	27801778
DrugRepV_0231	JB1a	NA	NA	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?4.02 ± 0.13 Ct)	NA	27801778
DrugRepV_0232	JB1a	NA	NA	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?5.48 ± 0.50 Ct)	NA	27801778
DrugRepV_0233	Omeprazole	Alimentary Tract and Metabolism	Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (1.35 ± 1.35 Ct)	Approved	27801778
DrugRepV_0234	Omeprazole	Alimentary Tract and Metabolism	Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (2.21 ± 1.08 Ct)	Approved	27801778
DrugRepV_0235	Esomeprazole Magnesium	Alimentary Tract and Metabolism	Acid-reflux disorders (GERD) and peptic ulcer disease	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (1.05 ± 0.79 Ct)	Approved	27801778
DrugRepV_0236	Esomeprazole Magnesium	Alimentary Tract and Metabolism	Acid-reflux disorders (GERD) and peptic ulcer disease	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (1.62 ± 0.36 Ct)	Approved	27801778
DrugRepV_0237	Gleevec	Antineoplastic and Immunomodulating Agents	Leukemia	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (3.60 ± 0.63 Ct)	Approved	27801778
DrugRepV_0238	Gleevec	Antineoplastic and Immunomodulating Agents	Leukemia	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (3.49 ± 0.54 Ct)	Approved	27801778
DrugRepV_0239	Aimspro	NA	Multiple sclerosis	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?2.03 ± 0.95 Ct)	Phase II	27801778
DrugRepV_0240	Aimspro	NA	Multiple sclerosis	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?4.60 ± 1.15 Ct)	Phase II	27801778
DrugRepV_0241	NCK-8	NA	NA	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (>10 Ct)	NA	27801778
DrugRepV_0242	NCK-8	NA	NA	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (>10 Ct)	NA	27801778
DrugRepV_0243	D-LANA-14	Antibacterial	Bacterial infections	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (>10 Ct)	NA	27801778
DrugRepV_0244	D-LANA-14	Antibacterial	Bacterial infections	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (>10 Ct)	NA	27801778
DrugRepV_0245	Tasigna	Antineoplastic and Immunomodulating Agents	Myeloid leukemia	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (3.59 ± 0.57 Ct)	Approved, Investigational	27801778
DrugRepV_0246	Tasigna	Antineoplastic and Immunomodulating Agents	Myeloid leukemia	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?0.13 ± 0.33 Ct)	Approved, Investigational	27801778
DrugRepV_0247	Celgosivir	Antiviral	Hepatitis C virus	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?2.52 ± 0.21 Ct)	Investigational	27801778
DrugRepV_0248	Celgosivir	Antiviral	Hepatitis C virus	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?2.41 ± 0.12 Ct)	Investigational	27801778
DrugRepV_0249	Castanospermine	Antiviral	Dengue and Parainfluenza	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?1.58 ± 3.23 Ct)	Experimental	27801778
DrugRepV_0250	Castanospermine	Antiviral	Dengue and Parainfluenza	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Increase (?0.26 ± 4.11 Ct)	Experimental	27801778
DrugRepV_0251	Ouabain	Cardiovascular agents	Atrial fibrillation and flutter | Heart failure	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (0.33 ± 0.35 Ct)	Approved	27801778
DrugRepV_0252	Alvespimycin	NA	Cancer	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (0.44 ± 0.06 Ct)	Investigational	27801778
DrugRepV_0253	Bemcentinib	Anticancer	Cancer	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (0.90 ± 0.15 Ct)	Investigational	27801778
DrugRepV_0254	Omeprazole	Alimentary Tract and Metabolism	Duodenal ulcers | Benign gastric ulcers | Gastroesophageal reflux disease (GERD) | Heartburn and other symptoms associated with GERD	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (0.86 ± 0.22 Ct)	Approved	27801778
DrugRepV_0255	Esomeprazole	Alimentary Tract and Metabolism	Acid-reflux disorders (GERD) and peptic ulcer disease	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (0.78 ± 0.25 Ct)	Approved	27801778
DrugRepV_0256	Gleevec	Antineoplastic and Immunomodulating Agents	Leukemia	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (1.55 ± 0.20 Ct)	Approved	27801778
DrugRepV_0257	NCK-8	NA	NA	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (1.54 ± 0.44 Ct)	NA	27801778
DrugRepV_0258	D-LANA-14	Antibacterial	Bacterial infections	Ebola virus	ME718-1976/Yambuku-Ecran	NA	Real-time PCR	Decrease (0.96 ± 0.19 Ct)	NA	27801778
DrugRepV_0266	Imatinib	Antineoplastic and Immunomodulating Agents	Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors	Severe acute respiratory syndrome coronavirus	MA15	NA	Real-time PCR	Decrease (>100 Fold)	Approved	27466418
DrugRepV_0267	Imatinib	Antineoplastic and Immunomodulating Agents	Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors	Severe acute respiratory syndrome coronavirus	MA15	NA	Real-time PCR	Decrease (>100 Fold)	Approved	27466418
DrugRepV_0268	Imatinib	Antineoplastic and Immunomodulating Agents	Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors	Middle East respiratory syndrome coronavirus	Hu/Jordan-N3/2012	NA	Real-time PCR	Decrease (>100 Fold)	Approved	27466418
DrugRepV_0269	Imatinib	Antineoplastic and Immunomodulating Agents	Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors	Middle East respiratory syndrome coronavirus	Hu/Jordan-N3/2012	NA	Real-time PCR	Decrease (>10 Fold)	Approved	27466418
DrugRepV_0290	Kaletra	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Middle East respiratory syndrome coronavirus	EMC/2012	NA	Real-time PCR	Decrease (1.06 Log10 Copies/GAPDH)	Approved, Investigational	26198719
DrugRepV_0292	Betaferon	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Middle East respiratory syndrome coronavirus	EMC/2012	NA	Real-time PCR	Decrease (0.59 Log10 Copies/GAPDH)	Approved	26198719
DrugRepV_0294	Mycophenolate Mofetil	Immunosuppressant	Organ rejection (immunosuppressants)	Middle East respiratory syndrome coronavirus	EMC/2012	NA	Real-time PCR	Increase (0.15 Log10 Copies/GAPDH)	Approved, Investigational	26198719
DrugRepV_0595	Clomiphene Citrate	Genito Urinary System and Sex Hormones	Female infertility	Ebola virus	EBOV/Kik	NA	Real-time PCR	Decrease (50 %)	Approved	23785035
DrugRepV_0596	Clomiphene Citrate	Genito Urinary System and Sex Hormones	Female infertility	Ebola virus	SUDV	NA	Real-time PCR	Decrease (50 %)	Approved	23785035
DrugRepV_0597	Clomiphene Citrate	Genito Urinary System and Sex Hormones	Female infertility	Ebola virus	MARV	NA	Real-time PCR	Decrease (50 %)	Approved	23785035
DrugRepV_0598	Toremifene Citrate	Antineoplastic and Immunomodulating Agents	Breast Cancer	Ebola virus	EBOV/Kik	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational	23785035
DrugRepV_0599	Toremifene Citrate	Antineoplastic and Immunomodulating Agents	Breast Cancer	Ebola virus	SUDV	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational	23785035
DrugRepV_0600	Toremifene Citrate	Antineoplastic and Immunomodulating Agents	Breast Cancer	Ebola virus	MARV	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational	23785035
DrugRepV_0629	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0630	Biperiden	Nervous System	Parkinson disease	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0631	Carprofen	Anti-inflammatory	Joint pain	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Withdrawn	23577127
DrugRepV_0632	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0633	Diphenylpyraline	Respiratory System	Allergies	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0634	Dipivefrin	Sensory Organ	Glaucoma	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0635	Dirithromycin	Antiinfectives For Systemic Use	Bacterial infections	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0636	Erythromycin	Antiinfectives For Systemic Use	Bacterial infections	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0637	Estradiol	Genito Urinary System and Sex Hormones	Vulvar and vaginal atrophy	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0638	Fluoxetine	Nervous System	Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Vet approved	23577127
DrugRepV_0639	Ketotifen	Respiratory System	Atopic asthma | Conjunctivitis	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0640	Mycophenolate Mofetil	Immunosuppressant	Organ rejection (immunosuppressants)	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Investigational	23577127
DrugRepV_0641	Oxyphencyclimine	Alimentary Tract and Metabolism	Peptic ulcers	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0642	Paroxetine	Nervous System	Major depressive disorder (MDD) | Panic disorder | Obsessive-compulsive disorder (OCD) | Social anxiety disorder (social phobia) | Generalized anxiety disorder (GAD) | Post-traumatic stress disorder (PTSD) | Premenstrual dysphoric disorder (PMDD)	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved, Investigational	23577127
DrugRepV_0643	Trihexyphenidyl	Nervous System	Parkinson Disease	Lassa virus	Josiah	NA	Real-time PCR	No significant effect	Approved	23577127
DrugRepV_0737	Probenecid	Musculo-Skeletal System	Gout	Influenza virus	A/WSN/33		Real-time PCR	Decrease (>4 Fold)	Approved, Investigational	23129053
DrugRepV_0738	Probenecid	Musculo-Skeletal System	Gout	Influenza virus	A/New/ Caledonia/20/99		Real-time PCR	Decrease (~10 Fold)	Approved, Investigational	23129053
DrugRepV_0739	Probenecid	Musculo-Skeletal System	Gout	Influenza virus	A/California/04/09		Real-time PCR	Decrease (2 Fold)	Approved, Investigational	23129053
DrugRepV_0749	Favipiravir	Antiviral	Influenza virus	Nipah virus	rNiV-Gluc-eGFP	NA	Real-time PCR	Decrease (10 Fold)	Investigational	29765101
DrugRepV_0751	Favipiravir	Antiviral	Influenza virus	Nipah virus	NiV-Malaysia	NA	Real-time PCR	Decrease (20,000 / 2,000 / 500 Fold)	Investigational	29765101
DrugRepV_0754	Favipiravir	Antiviral	Influenza virus	Nipah virus	NiV-Malaysia	NA	Real-time PCR	Decrease (30,000 / 300 / 100 Fold)	Investigational	29765101
DrugRepV_0757	Favipiravir	Antiviral	Influenza virus	Ebola virus	NA	NA	Real-time PCR	No significant effect	Investigational	26930627
DrugRepV_0759	Favipiravir	Antiviral	Influenza virus	Ebola virus	NA	NA	Real-time PCR	Decrease	Investigational	26930627
DrugRepV_1588	Sorafenib	Antineoplastic and Immunomodulating Agents	Hepatocellular carcinoma | Renal cell carcinoma	Rift Valley fever virus	NA	NA	Real-time PCR	Decrease	Approved, Investigational	26217313
DrugRepV_1611	Sorafenib	Antineoplastic and Immunomodulating Agents	Hepatocellular carcinoma | Renal cell carcinoma	Rift Valley fever virus	ZH501	NA	Real-time PCR	Decrease (2 Logs reduction)	Approved, Investigational	26217313
DrugRepV_1612	Sorafenib	Antineoplastic and Immunomodulating Agents	Hepatocellular carcinoma | Renal cell carcinoma	Rift Valley fever virus	ZH501	NA	Real-time PCR	Decrease (2 Logs reduction)	Approved, Investigational	26217313
DrugRepV_1613	Sorafenib	Antineoplastic and Immunomodulating Agents	Hepatocellular carcinoma | Renal cell carcinoma	Rift Valley fever virus	ZH501	NA	Real-time PCR	Decrease (0.4 Logs reduction)	Approved, Investigational	26217313
DrugRepV_1884	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Zika virus	FSS13025	NA	Real-time PCR	Decrease (50 %)	Approved	27571349
DrugRepV_1885	PHA-690509	NA	Cancer	Zika virus	FSS13026	NA	Real-time PCR	Decrease (50 %)	NA	27571349
DrugRepV_1886	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Zika virus	FSS13025	NA	Real-time PCR	Decrease	Approved	27571349
DrugRepV_1887	PHA-690509	NA	Cancer	Zika virus	FSS13026	NA	Real-time PCR	Decrease	NA	27571349
DrugRepV_1919	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	PLCal_ZV	NA	Real-time PCR	Decrease (85.7 %)	Approved	29315671
DrugRepV_1920	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Zika virus	PLCal_ZV	NA	Real-time PCR	Decrease (99 %)	Approved	29315671
DrugRepV_1921	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Zika virus	PLCal_ZV	NA	Real-time PCR	Decrease (85.7 %)	Approved	29315671
DrugRepV_1931	Manidipine	Cardiovascular agents	Hypertension	Zika virus	H/PF/2013	NA	Real-time PCR	Decrease (0 %)	Approved, Investigational	28814523
DrugRepV_1932	Cilnidipine	Cardiovascular agents	Hypertension	Zika virus	H/PF/2013	NA	Real-time PCR	Decrease (0.01 %)	Approved	28814523
DrugRepV_1933	Benidipine Hydrochloride	Cardiovascular agents	Hypertension	Zika virus	H/PF/2013	NA	Real-time PCR	Decrease (0.03 %)	Approved	28814523
DrugRepV_1934	Pimecrolimus	Dermatologicals	Atopic dermatitis	Zika virus	H/PF/2013	NA	Real-time PCR	Decrease (0.2 %)	Approved, Investigational	28814523
DrugRepV_1935	Nelfinavir Mesylate	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Zika virus	H/PF/2013	NA	Real-time PCR	Decrease (0 %)	Approved	28814523
DrugRepV_1944	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (98 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1945	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease	Approved, Investigational, Vet approved	28480282
DrugRepV_1946	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1947	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease	Approved, Investigational, Vet approved	28480282
DrugRepV_1948	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1949	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1950	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (98 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1951	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1955	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (98 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1956	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease	Approved, Investigational, Vet approved	28480282
DrugRepV_1957	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease	Approved, Investigational, Vet approved	28480282
DrugRepV_1958	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease	Approved, Investigational, Vet approved	28480282
DrugRepV_1959	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease	Approved, Investigational, Vet approved	28480282
DrugRepV_1960	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1961	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1962	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (98 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_1963	Tizoxanide	Antiparasitic products, Insectisides and Repellents	Crytosporidiosis and Giardiasis	Zika virus	SZ-WIV01	NA	Real-time PCR	Decrease (100 %)	Approved, Investigational, Vet approved	28480282
DrugRepV_2054	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Chikungunya virus	S27	NA	Real-time PCR	Decrease (50 %)	Approved	27742486
DrugRepV_2055	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Chikungunya virus	S27	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational, Vet approved	27742486
DrugRepV_2058	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Chikungunya virus	0611aTw	NA	Real-time PCR	Decrease (50 %)	Approved	27742486
DrugRepV_2059	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Chikungunya virus	0611aTw	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational, Vet approved	27742486
DrugRepV_2060	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Chikungunya virus	081bTw	NA	Real-time PCR	Decrease (50 %)	Approved	27742486
DrugRepV_2061	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Chikungunya virus	081bTw	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational, Vet approved	27742486
DrugRepV_2062	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Chikungunya virus	S27	NA	Real-time PCR	Decrease (50 %)	Approved	27742486
DrugRepV_2063	Nitazoxanide	Antiparasitic products, Insectisides and Repellents	Diarrhea	Chikungunya virus	S27	NA	Real-time PCR	Decrease (50 %)	Approved, Investigational, Vet approved	27742486
DrugRepV_2068	Niclosamide	Antiparasitic products, Insectisides and Repellents	Tapeworm and intestinal fluke infections | Helminthiasis	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease	Approved	15215127
DrugRepV_2109	NITD008	Antiviral	NA	Zika virus	GZ01/2016	NA	Real-time PCR	Decrease (50 %)	NA	27747251
DrugRepV_2110	NITD008	Antiviral	NA	Zika virus	FSS13025/2010	NA	Real-time PCR	Decrease (50 %)	NA	27747251
DrugRepV_2112	NITD008	Antiviral	NA	Zika virus	GZ01/2016	NA	Real-time PCR	Decrease (2.6 Fold)	NA	27747251
DrugRepV_2119	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Zika virus	PRVABC-59	NA	Real-time PCR	Decrease (>1 Log10 (GE/ml))	Approved	27902933
DrugRepV_2120	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Zika virus	PRVABC-59	NA	Real-time PCR	Decrease (2 Log10 (GE/ml))	Approved	27902933
DrugRepV_2121	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Zika virus	Paraiba	NA	Real-time PCR	Decrease (>1 Log10 (GE/ml))	Approved	27902933
DrugRepV_2122	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Zika virus	Paraiba	NA	Real-time PCR	Decrease (2 Log10 (GE/ml))	Approved	27902933
DrugRepV_2123	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Zika virus	Dakar	NA	Real-time PCR	Decrease (>1 Log10 (GE/ml))	Approved	27902933
DrugRepV_2124	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Zika virus	Dakar	NA	Real-time PCR	Decrease (>2 Log10 (GE/ml))	Approved	27902933
DrugRepV_2139	7-deaza-2-C-methyl-D-adenosine	NA	Viral infection	Zika virus	MR766	NA	Real-time PCR	Decrease	NA	27163257
DrugRepV_2948	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Chikungunya virus	DRDE-06	NA	Real-time PCR	Decrease	Approved	20336760
DrugRepV_2949	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Chikungunya virus	DRDE-06	NA	Real-time PCR	Decrease	Approved	20336760
DrugRepV_2950	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Chikungunya virus	DRDE-06	NA	Real-time PCR	Decrease	Approved	20336760
DrugRepV_3002	Imipramine	Nervous System	Depression	Chikungunya virus	La Reunion strain	NA	Real-time PCR	Decrease (100 %)	Approved	28600536
DrugRepV_3008	Imipramine	Nervous System	Depression	Chikungunya virus	La Reunion strain	NA	Real-time PCR	Decrease (1x 103 logs)	Approved	28600536
DrugRepV_3009	Imipramine	Nervous System	Depression	Zika virus	Pf13	NA	Real-time PCR	Decrease (100 %)	Approved	28600536
DrugRepV_3012	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Zika virus	HD78788	NA	Real-time PCR	Decrease	Approved	28343845
DrugRepV_3013	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Zika virus	HD78788	NA	Real-time PCR	Decrease (0.8 log)	Approved	28343845
DrugRepV_3014	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Chikungunya virus	La Reunion strain, 06-049 AM258994	NA	Real-time PCR	Decrease (1 log)	Approved	28343845
DrugRepV_3015	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Zika virus	HD78788	NA	Real-time PCR	Decrease (1 log)	Approved	28343845
DrugRepV_3016	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Zika virus	HD78788	NA	Real-time PCR	Decrease (1 log)	Approved	28343845
DrugRepV_3017	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Chikungunya virus	La Reunion strain, 06-049 AM258994	NA	Real-time PCR	Decrease (0.7 log)	Approved	28343845
DrugRepV_3018	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Chikungunya virus	La Reunion strain, 06-049 AM258994	NA	Real-time PCR	Decrease (0.8 log)	Approved	28343845
DrugRepV_3019	Curcumin	NA	Cancer, mucositis, chronic schizophrenia and mild cognitive impairment	Chikungunya virus	La Reunion strain, 06-049 AM258994	NA	Real-time PCR	Decrease (0.5 log)	Approved	28343845
DrugRepV_3145	Harringtonine	NA	NA	Chikungunya virus	CHIKV-0708	NA	Real-time PCR	Decrease (6 (Complete inhibition) Log)	NA	23275491
DrugRepV_3146	Harringtonine	NA	NA	Chikungunya virus	CHIKV-0708	NA	Real-time PCR	Decrease (2 Log)	NA	23275491
DrugRepV_3147	Harringtonine	NA	NA	Chikungunya virus	CHIKV-0708	NA	Real-time PCR	Decrease (2 Log)	NA	23275491
DrugRepV_3148	Harringtonine	NA	NA	Chikungunya virus	CHIKV-122508	NA	Real-time PCR	Decrease (2.4 Log)	NA	23275491
DrugRepV_3149	Harringtonine	NA	NA	Chikungunya virus	CHIKV-122508	NA	Real-time PCR	Decrease (3 Log)	NA	23275491
DrugRepV_3179	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Chikungunya virus	DRDE-06	NA	Real-time PCR	Decrease	Approved	21070810
DrugRepV_3180	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Chikungunya virus	DRDE-06	NA	Real-time PCR	Decrease	Approved	21070810
DrugRepV_3211	Andrographolide	NA	Ulcerative colitis and Upper respiratory tract infection	Chikungunya virus	E1:226VT	NA	Real-time PCR	Decrease (2 Log)	Investigational	26384169
DrugRepV_3212	Andrographolide	NA	Ulcerative colitis and Upper respiratory tract infection	Chikungunya virus	E1:226AS	NA	Real-time PCR	Decrease (2 Log)	Investigational	26384169
DrugRepV_3232	Andrographolide	NA	Ulcerative colitis and Upper respiratory tract infection	Chikungunya virus	E1:226AS	NA	Real-time PCR	Decrease (2 Log)	Investigational	26384169
DrugRepV_3242	Favipiravir	Antiviral	Influenza virus	Chikungunya virus	Indian Ocean strain 899	NA	Real-time PCR	Decrease (50 %)	Investigational	24951535
DrugRepV_3249	T-1105	NA	Zika virus	Chikungunya virus	Indian Ocean strain 899	NA	Real-time PCR	Decrease (50 %)	NA	24951535
DrugRepV_3250	T-1105	NA	Zika virus	Chikungunya virus	LR2006 OPY1	NA	Real-time PCR	Decrease (50 %)	NA	24951535
DrugRepV_3251	T-1105	NA	Zika virus	Chikungunya virus	Venturini (Italy 2008)	NA	Real-time PCR	Decrease (50 %)	NA	24951535
DrugRepV_3252	T-1105	NA	Zika virus	Chikungunya virus	Bianchi (Italy 2008)	NA	Real-time PCR	Decrease (50 %)	NA	24951535
DrugRepV_3253	T-1105	NA	Zika virus	Chikungunya virus	Congo 95 (2011)	NA	Real-time PCR	Decrease (50 %)	NA	24951535
DrugRepV_3254	Favipiravir	Antiviral	Influenza virus	Chikungunya virus	CHIKV 899	NA	Real-time PCR	Decrease (95 %)	Investigational	24951535
DrugRepV_3255	Favipiravir	Antiviral	Influenza virus	Chikungunya virus	CHIKV 899	NA	Real-time PCR	Decrease (98 %)	Investigational	24951535
DrugRepV_3256	Favipiravir	Antiviral	Influenza virus	Chikungunya virus	CHIKV 899	NA	Real-time PCR	Decrease (88 %)	Investigational	24951535
DrugRepV_3259	Favipiravir	Antiviral	Influenza virus	Chikungunya virus	CHIKV S27	NA	Real-time PCR	Decrease (3.2 ± 0.1 Log)	Investigational	24951535
DrugRepV_3260	Favipiravir	Antiviral	Influenza virus	Chikungunya virus	CHIKV S27	NA	Real-time PCR	Decrease (2.3 ± 0.3 Log)	Investigational	24951535
DrugRepV_3303	Cerulenin	NA	Fungal infection	Chikungunya virus	NA	NA	Real-time PCR	Decrease (100 %)	Approved	27177310
DrugRepV_3304	5-Tetradecyloxy-2-furoic Acid	NA	NA	Chikungunya virus	NA	NA	Real-time PCR	Decrease (100 %)	NA	27177310
DrugRepV_3305	Pimozide	Nervous System	Tourette Disorder	Chikungunya virus	NA	NA	Real-time PCR	Decrease (75 %)	Approved	27177310
DrugRepV_3306	TIvozanib	NA	Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease	Chikungunya virus	NA	NA	Real-time PCR	Decrease (50 %)	Investigational	27177310
DrugRepV_3307	Cerulenin	NA	Fungal infection	Chikungunya virus	NA	NA	Real-time PCR	Decrease (100 %)	Approved	27177310
DrugRepV_3308	5-Tetradecyloxy-2-furoic Acid	NA	NA	Chikungunya virus	NA	NA	Real-time PCR	Decrease (100 %)	NA	27177310
DrugRepV_3309	Pimozide	Nervous System	Tourette Disorder	Chikungunya virus	NA	NA	Real-time PCR	Decrease (80 %)	Approved	27177310
DrugRepV_3310	TIvozanib	NA	Solid Tumors, Glioblastoma, Ovarian Cancer, Prostate Cancer, and Stage IV Disease	Chikungunya virus	NA	NA	Real-time PCR	Decrease (80 %)	Investigational	27177310
DrugRepV_3325	Naproxen	Musculo-Skeletal System	Rheumatoid arthritis | Osteoarthritis | Ankylosing spondylitis | Polyarticular juvenile idiopathic arthritis | Tendinitis | Bursitis | Acute gout | Primary dysmenorrhea	Influenza virus	A/WSN/33		Real-time PCR	Decrease (50 %)	Approved	23459490
DrugRepV_3395	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Middle East respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (>2 Log)	Approved	24096239
DrugRepV_3396	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Middle East respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (>2 Log)	Approved	24096239
DrugRepV_3397	Rebif	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Middle East respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (>2 Log)	Approved	24096239
DrugRepV_3398	Betaferon	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Middle East respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (>2 Log)	Approved	24096239
DrugRepV_3399	Betaferon	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Middle East respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (>1 Log)	Approved	24096239
DrugRepV_3400	Betaferon	Antineoplastic and Immunomodulating Agents	Multiple sclerosis	Middle East respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (>3 Log)	Approved	24096239
DrugRepV_3544	Carbinoxamine maleate	Respiratory System	Allergic rhinitis, vasomotor rhinitis and allergic conjunctivitis	Influenza virus	A/PR/8/1934 (H1N1)		Real-time PCR	Decrease (90 %)	Approved	30459739
DrugRepV_3545	Chlorpheniramine Maleate	Respiratory System	Allergic reactions | Hay fever | Rhinitis | Urticaria | Asthma	Influenza virus	A/PR/8/1934 (H1N1)		Real-time PCR	Decrease (80 %)	Approved	30459739
DrugRepV_3550	Sofosbuvir	Antiinfectives For Systemic Use	Hepatitis C virus | Acquired immunodeficiency syndrome	Chikungunya virus	Asian strain	NA	Real-time PCR	Decrease (50 %)	Approved	30455237
DrugRepV_3552	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Chikungunya virus	Asian strain	NA	Real-time PCR	Decrease (50 %)	Approved	30455237
DrugRepV_3554	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Chikungunya virus	Asian strain	NA	Real-time PCR	Decrease (50 %)	Approved	30455237
DrugRepV_5076	Favipiravir	Antiviral	Influenza virus	Crimean-Congo hemorrhagic fever virus	10200	NA	Real-time PCR	Decrease	Investigational	29936152
DrugRepV_5077	Favipiravir	Antiviral	Influenza virus	Crimean-Congo hemorrhagic fever virus	Hoti	NA	Real-time PCR	Decrease	Investigational	29936152
DrugRepV_5080	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Crimean-Congo hemorrhagic fever virus	10200	NA	Real-time PCR	Decrease	Approved	29936152
DrugRepV_5081	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Crimean-Congo hemorrhagic fever virus	Hoti	NA	Real-time PCR	Decrease	Approved	29936152
DrugRepV_5082	Ribavirin	Antiinfectives For Systemic Use	Hepatitis C virus	Crimean-Congo hemorrhagic fever virus	NA	NA	Real-time PCR	Decrease (100 Copies/ml)	Approved	29584885
DrugRepV_5091	S-Nitroso-N-acetylpenicillamine	NA	NA	Crimean-Congo hemorrhagic fever virus	IbAr 10200	NA	Real-time PCR	Decrease	NA	16632039
DrugRepV_5096	IFN-alpha	Antiviral	Hepatitis C virus | Leukemia | Melanoma	Crimean-Congo hemorrhagic fever virus	IbAr 10200	NA	Real-time PCR	Decrease	Investigational	16372299
DrugRepV_5097	IFN-alpha	Antiviral	Hepatitis C virus | Leukemia | Melanoma	Crimean-Congo hemorrhagic fever virus	IbAr 10200	NA	Real-time PCR	No significant effect	Investigational	16372299
DrugRepV_5169	Rapamycin	Antineoplastic and Immunomodulating Agents; Sensory Organ	Prophylaxis of organ rejection in patients receiving renal transplants	Rift Valley fever virus	MP12	NA	Real-time PCR	Decrease (2 log Genomic Copies)	Approved, Investigational	28442428
DrugRepV_5273	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5274	diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5275	diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5276	1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5277	2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5278	1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5279	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5280	{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5281	4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5282	4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5283	4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5284	4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5285	4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5286	4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5287	1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5288	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5289	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5290	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5291	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5292	diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5293	diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5294	1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5295	2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5296	1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5297	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5298	{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5299	4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5300	4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5301	4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5302	4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5303	4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5304	4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5305	1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5306	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5307	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5308	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide	NA	NA	Lassa virus	AV	NA	Real-time PCR	Decrease (90 %)	NA	15451189
DrugRepV_5309	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5310	diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5311	diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5312	1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5313	2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5314	1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5315	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5316	{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5317	4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5318	4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5319	4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5320	4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5321	4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5322	4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5323	1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5324	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5325	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5326	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide	NA	NA	Severe acute respiratory syndrome coronavirus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5327	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarbonitrile	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5328	diethyl {[2-(4,5-dicyano-1H-imidazol-1-yl)ethoxy]methyl}phosphonate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5329	diethyl {2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl}phosphonate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5330	1-[(2-bromoethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5331	2-[(4,5-dicyano-1H-imidazol-1-yl)methoxy]ethyl acetate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5332	1-[(2-hydroxyethoxy)methyl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5333	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbonitrile	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5334	{2-[4,5-bis(methoxycarbonyl)-1H-imidazol-1-yl]ethoxy}phosphonic acid	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5335	4,5-dimethyl 1-[(2R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5336	4,5-dimethyl 1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5337	4,5-dimethyl 1-[2-(acetyloxy)ethyl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5338	4,5-dimethyl 1-[(2R,5S)-3,4-bis(acetyloxy)-5-[(acetyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5339	4,5-dimethyl 1-[(2R,5S)-3,4-bis(benzoyloxy)-5-[(benzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5340	4,5-dimethyl 1-[(2R,5S)-4-(4-methylbenzoyloxy)-5-[(4-methylbenzoyloxy)methyl]oxolan-2-yl]-1H-imidazole-4,5-dicarboxylate	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5341	1-(2-hydroxyethyl)-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5342	1-{[2-(benzyloxy)ethoxy]methyl}-1H-imidazole-4,5-dicarboxylic acid	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5343	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarbohydrazide	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5344	1-[(2R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4,5-dicarboxamide	NA	NA	Ebola virus	NA	NA	Real-time PCR	Decrease (50 %)	NA	15451189
DrugRepV_5602	Sunitinib	Antineoplastic and Immunomodulating Agents	Renal cell carcinoma | Gastrointestinal stromal tumor	Dengue virus	N124D/K128E		Real-time PCR	No significant effect	Approved, Investigational	28240606
DrugRepV_5603	Erlotinib	Antineoplastic and Immunomodulating Agents	Cancer	Dengue virus	N124D/K128E		Real-time PCR	No significant effect	Approved	28240606
DrugRepV_5605	Sunitinib-Erlotinib	NA	NA	Dengue virus	N124D/K128E		Real-time PCR	Decrease (11 Fold)	NA	28240606
DrugRepV_5627	Nanchangmycin	Antibacterial; Antiviral	NA	Dengue virus	New Guinea C		Real-time PCR	Decrease (95 %)	NA	28099856
DrugRepV_5632	Minocycline	Antiinfectives For Systemic Use	Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae	Dengue virus	16681		Real-time PCR	Decrease (50 %)	Approved, Investigational	27396621
DrugRepV_5651	Celgosivir	Antiviral	Hepatitis C virus	Dengue virus	DENV1-2402		Real-time PCR	Decrease (4.3 Fold)	Phase II	26794905
DrugRepV_5652	Celgosivir	Antiviral	Hepatitis C virus	Dengue virus	DENV2-3295		Real-time PCR	Decrease (16.5 Fold)	Phase II	26794905
DrugRepV_5653	Celgosivir	Antiviral	Hepatitis C virus	Dengue virus	S221		Real-time PCR	Decrease (2.4 Fold)	Phase II	26794905
DrugRepV_5654	Celgosivir	Antiviral	Hepatitis C virus	Dengue virus	DENV1-2402		Real-time PCR	Decrease (0.5 Log (copies/ml))	Phase II	26794905
DrugRepV_5655	Celgosivir	Antiviral	Hepatitis C virus	Dengue virus	DENV2-3295		Real-time PCR	Decrease (2 Log (copies/ml))	Phase II	26794905
DrugRepV_5676	Bortezomib	Antineoplastic and Immunomodulating Agents	Multiple Myeloma	Dengue virus	EDEN 3295		Real-time PCR	Decrease	Approved	26565697
DrugRepV_5677	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	Thsman		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5678	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	FR37 -clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5679	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	FR42-clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5680	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	FR28 -clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5681	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	FR34 -clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5682	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	Th36		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5683	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	32/0140 --clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5684	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	32/0102--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5685	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	33/0178--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5686	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	33/0051--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5687	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	H87		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5688	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	33/0072--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5689	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	33/0253--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5690	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	33/0177--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5691	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	33/0096--clinical isolate from Vietnamese dengue patients		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5692	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	H241		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5693	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	Phili/1567- patient strain as gift		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5694	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	Venz/JQ - patient strain as gift		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5695	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	Senga/DA - patient strain as gift		Real-time PCR	Decrease (50 %)	Phase II failed	22807519
DrugRepV_5696	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	NA		Real-time PCR	Increase (0.2 Log10 Copies/ml)	Phase II failed	22807519
DrugRepV_5697	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	NA		Real-time PCR	Increase (0.5 Log10 Copies/ml)	Phase II failed	22807519
DrugRepV_5698	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	NA		Real-time PCR	No significant effect (0.7 Log10 Copies/ml)	Phase II failed	22807519
DrugRepV_5699	Balapiravir	Antiviral	Hepatitis C virus	Dengue virus	NA		Real-time PCR	Increase (0.3 Log10 Copies/ml)	Phase II failed	22807519
DrugRepV_5705	Mycophenolic Acid	Antineoplastic and Immunomodulating Agents	Organ rejection (immunosuppressants)	Dengue virus	16681		Real-time PCR	Decrease (>100 Fold)	Approved	12504563
DrugRepV_5745	Boceprevir	Antiinfectives For Systemic Use	Hepatitis C virus	Dengue virus	DV2-NGC		Real-time PCR	No significant effect	Phase II	29297305
DrugRepV_5746	Telaprevir	Antiinfectives For Systemic Use	Hepatitis C virus	Dengue virus	DV2-NGC		Real-time PCR	Decrease (2 Logs)	Approved	29297305
DrugRepV_5747	Asunaprevir	Antiinfectives For Systemic Use	Hepatitis C virus	Dengue virus	DV2-NGC		Real-time PCR	Decrease (5 Logs)	Phase III	29297305
DrugRepV_5792	Lanatoside C	Cardiovascular agents	Arrhythmia	Dengue virus	Singapore isolates (+)		Real-time PCR	Decrease (2 Logs)	Experimental	25251726
DrugRepV_5793	Lanatoside C	Cardiovascular agents	Arrhythmia	Dengue virus	Singapore isolates (-)		Real-time PCR	Decrease (2 Logs)	Experimental	25251726
DrugRepV_5800	Geneticin	Antibacterial	Bacterial infections	Dengue virus	NA		Real-time PCR	Decrease (90 %)	Experimental	19501253
DrugRepV_5857	Narasin	Antibacterial	Parasitic and bacterial infections	Dengue virus	NA		Real-time PCR	No significant effect (0 Copies number)	Experimental	22155902
DrugRepV_5866	N-Desmethylclozapine	Antipsychotic	Schizophrenia | Schizoaffective disorders	Dengue virus	NA		Real-time PCR	Decrease (10 Fold)	Investigational	27572397
DrugRepV_5867	Fluoxetine	Nervous System	Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia	Dengue virus	NA		Real-time PCR	Decrease (4.5 Fold)	Approved, Vet approved	27572397
DrugRepV_5868	Salmeterol	Respiratory System	Asthma | Chronic obstructive pulmonary disease	Dengue virus	NA		Real-time PCR	Decrease (99 Fold)	Approved	27572397
DrugRepV_5872	N-Desmethylclozapine	Antipsychotic	Schizophrenia | Schizoaffective disorders	Dengue virus	NA		Real-time PCR	Decrease (>75 Fold)	Investigational	27572397
DrugRepV_5873	Fluoxetine	Nervous System	Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia	Dengue virus	NA		Real-time PCR	Decrease (<10 Fold)	Approved, Vet approved	27572397
DrugRepV_5874	Salmeterol	Respiratory System	Asthma | Chronic obstructive pulmonary disease	Dengue virus	NA		Real-time PCR	Decrease (<10 Fold)	Approved	27572397
DrugRepV_5878	N-Desmethylclozapine	Antipsychotic	Schizophrenia | Schizoaffective disorders	Dengue virus	NA		Real-time PCR	Decrease (> 90 %)	Investigational	27572397
DrugRepV_5879	Fluoxetine	Nervous System	Major depressive disorder | Bulimia nervosa | Obsessive-compulsive disorder | Premenstrual dysphoric disorder | Panic disorder with or without agoraphobia	Dengue virus	NA		Real-time PCR	Decrease (> 80 %)	Approved, Vet approved	27572397
DrugRepV_5880	Salmeterol	Respiratory System	Asthma | Chronic obstructive pulmonary disease	Dengue virus	NA		Real-time PCR	Decrease (> 95 %)	Approved	27572397
DrugRepV_5914	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Dengue virus	NA		Real-time PCR	Decrease (90 %)	Approved	24680954
DrugRepV_5915	Amodiaquine	Antiparasitic products, Insectisides and Repellents	Malaria	Dengue virus	NA		Real-time PCR	Decrease (90 %)	Approved	24680954
DrugRepV_5971	Chloroquine	Antiparasitic products, Insectisides and Repellents	Malaria	Dengue virus	New Guinea		Real-time PCR	Decrease	Approved	24773578
DrugRepV_6004	Imipramine	Nervous System	Depression	Dengue virus	16681		Real-time PCR	Decrease (100 %)	Approved	28600536
DrugRepV_6017	N-nonyl-deoxynojirimycin	NA	NA	Dengue virus	PL046		Real-time PCR	Decrease (Decrease Ct Value)	NA	11907199
DrugRepV_6018	N-nonyl-deoxynojirimycin	NA	NA	Dengue virus	PL046		Real-time PCR	Decrease (Decrease Ct Value)	NA	11907199
DrugRepV_6500	Decitabine	NA	Myelodysplastic syndromes +Different types of Cancer	Human immunodeficiency virus	NA		Real-time PCR	Decrease	NA	20610712
DrugRepV_7004	Nanchangmycin	Antibacterial; Antiviral	NA	West Nile virus	Kunjin		Real-time PCR	Decrease (95 %)	NA	28099856
DrugRepV_7021	Manidipine	Cardiovascular agents	Hypertension	Japanese encephalitis virus	AT31		Real-time PCR	Decrease (0.01 %)	Approved, Investigational	28814523
DrugRepV_7022	Cilnidipine	Cardiovascular agents	Hypertension	Japanese encephalitis virus	AT31		Real-time PCR	Decrease (0.01 %)	Approved	28814523
DrugRepV_7023	Benidipine Hydrochloride	Cardiovascular agents	Hypertension	Japanese encephalitis virus	AT31		Real-time PCR	Decrease (0.01 %)	Approved	28814523
DrugRepV_7024	Pimecrolimus	Dermatologicals	Atopic dermatitis	Japanese encephalitis virus	AT31		Real-time PCR	Decrease (0.01 %)	Approved, Investigational	28814523
DrugRepV_7025	Nelfinavir Mesylate	Antiinfectives For Systemic Use	Acquired immunodeficiency syndrome	Japanese encephalitis virus	AT31		Real-time PCR	Decrease (0.1 %)	NA	28814523
DrugRepV_7057	Fenretinide	Anticancer	Prostate cancer | Breast cancer | Macular degeneration	West Nile virus	NA		Real-time PCR	Decrease (2 Fold)	Investigational	25313218
DrugRepV_7095	Imipramine	Nervous System	Depression	West Nile virus	WT		Real-time PCR	Decrease (100 %)	Approved	28600536
DrugRepV_7346	Baicalein	Plant extract	Influenza	Japanese encephalitis virus	HE861351		Real-time PCR	Decrease (68.46 ± 1.19 %)	Phase II	23222683
DrugRepV_7347	Quercetin	Antioxidant	NA	Japanese encephalitis virus	HE861351		Real-time PCR	Decrease (9.1 ± 0.2 %)	Experimental, Investigational	23222683